PDBsum entry 3zin

Transport protein/hydrolase

PDB id: 3zin

Contents

Protein chains

426 a.a.

13 a.a.

Ligands

GLN-LYS-ARG-SER-PHE-SER

Waters ×188

PDB id:

3zin

Name:

Transport protein/hydrolase

Title:

Gu_alpha_helicase

Structure:

Importin subunit alpha-2. Chain: a. Fragment: residues 72-496. Synonym: importin alpha p1, karyopherin subunit alpha-2, pendulin, pore targeting complex 58 kda subunit, ptac58, rag cohort protein 1, srp1-alpha, importin alpha_ibb. Engineered: yes. Nucleolar RNA helicase 2. Chain: b, c.

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.00Å R-factor: 0.180 R-free: 0.199

Authors:

C.-W.Chang,R.M.Counago,S.J.Williams,B.Kobe

Key ref:

C.W.Chang et al. (2013). Distinctive conformation of minor site-specific nuclear localization signals bound to importin-α. Traffic, 14, 1144-1154. PubMed id: 23910026 DOI: 10.1111/tra.12098

Date:

10-Jan-13 Release date: 21-Aug-13

Protein chain

P52293  (IMA1_MOUSE) -  Importin subunit alpha-1 from Mus musculus

Seq: 529 a.a.

Struc: 426 a.a.

Protein chain

Q9JIK5  (DDX21_MOUSE) -  Nucleolar RNA helicase 2 from Mus musculus

Seq: 851 a.a.

Struc: 13 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: Chain B: E.C.3.6.4.13 - Rna helicase.
• Reaction: ATP + H2O = ADP + phosphate + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

DOI no: 10.1111/tra.12098

Traffic 14:1144-1154 (2013)

PubMed id: 23910026

Distinctive conformation of minor site-specific nuclear localization signals bound to importin-α.

C.W.Chang, R.M.Couñago, S.J.Williams, M.Bodén, B.Kobe.

ABSTRACT

No abstract given.