UniProt functional annotation for P51834

UniProt code: P51834.

Organism: Bacillus subtilis (strain 168).
Taxonomy: Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
 
Function: Required for chromosome condensation and partitioning. {ECO:0000255|HAMAP-Rule:MF_01894, ECO:0000269|PubMed:9573042, ECO:0000269|PubMed:9701812}.
 
Subunit: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01894}.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01894, ECO:0000269|PubMed:9573042}. Note=Probably associated with the nucleoid.
Domain: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible SMC hinge near the middle of the molecule. These domains are separated by coiled- coil structures. {ECO:0000255|HAMAP-Rule:MF_01894}.
Disruption phenotype: Mutants produce anucleate cells and show defects in nucleoid structure and in chromosome partitioning. {ECO:0000269|PubMed:9573042, ECO:0000269|PubMed:9701812}.
Similarity: Belongs to the SMC family. {ECO:0000255|HAMAP- Rule:MF_01894}.

Annotations taken from UniProtKB at the EBI.