UniProt functional annotation for P30694

UniProt code: P30694.

Organism: Flaveria trinervia (Clustered yellowtops) (Oedera trinervia).
Taxonomy: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Heliantheae alliance; Tageteae; Flaveria.
 
Function: Forms oxaloacetate through the carboxylation of phosphoenolpyruvate (PEP). Catalyzes the first step of C4 photosynthesis.
 
Catalytic activity: Phosphate + oxaloacetate = H(2)O + phosphoenolpyruvate + HCO(3)(-).
Cofactor: Magnesium (By similarity).
Enzyme regulation: 5 fold activation by the allosteric regulator glucose-6-phosphate. Low sensitivity to inhibition by L-malate. Up-regulated by light-reversible phosphorylation (By similarity).
Biophysicochemical properties: Kinetic parameters: Vmax=27 umol/min/mg enzyme;
Pathway: Photosynthesis; C4 acid pathway.
Subunit: Homotetramer.
Subcellular location: Cytoplasm (By similarity).
Tissue specificity: Expressed in mesophyll cells, but not in bundle-sheath, roots, stems and flowers.
Domain: Region 2 (296-437) and region 5 (645-966) are involved in the acquisition of C4-specific properties. Region 5 (645-966) is involved in L-malate tolerance.
Miscellaneous: Ser-774 is strongly involved in determining allosteric behavior of C4 PEPC.
Similarity: Belongs to the PEPCase type 1 family.

Annotations taken from UniProtKB at the EBI.