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UniProt functional annotation for Q9H4M3 | ||
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| UniProt code: Q9H4M3. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. |
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| Subunit: | |
Part of a SCF (SKP1-cullin-F-box) protein ligase complex. Interacts with SKP1 and CUL1. {ECO:0000269|PubMed:18203720}. |
| Tissue specificity: | |
Abundantly expressed in brain and kidney. Expressed at lower levels in heart, spleen and liver. {ECO:0000269|PubMed:12383498}. |
| Miscellaneous: | |
In contrast to other FBA domain containing proteins, FBXO44 demonstrates no significant binding to any of the 200 glycans tested. |
Annotations taken from UniProtKB at the EBI.