PDBsum entry 3v94

Hydrolase/hydrolase inhibitor

PDB id: 3v94

Contents

Protein chains

(+ 2 more) 332 a.a.

Ligands

WYQ ×8

Metals

_MG ×8

_ZN ×8

Waters ×857

PDB id:

3v94

Name:

Hydrolase/hydrolase inhibitor

Title:

Tcrpdec1 catalytic domain in complex with inhibitor wyq16

Structure:

Cyclic nucleotide specific phosphodiesterase. Chain: a, b, c, d, e, f, g, h. Fragment: caatalytic domain. Engineered: yes

Source:

Trypanosoma cruzi. Organism_taxid: 5693. Strain: trypanosoma cruzi. Gene: pdec, tcrpdec1. Expressed in: escherichia coli. Expression_system_taxid: 511693.

Resolution:

2.33Å R-factor: 0.224 R-free: 0.268

Authors:

H.Wang,S.Kunz,G.Chen,T.Seebeck,Y.Wan,H.Robinson,S.Martinelli,H.Ke

Key ref:

H.Wang et al. Tcrpdec1 catalytic domain in complex with inhibitor w. To be published, .

Date:

23-Dec-11 Release date: 22-Feb-12

Protein chains

Q53I60  (Q53I60_TRYCR) -  Phosphodiesterase from Trypanosoma cruzi

Seq: 924 a.a.

Struc: 332 a.a.

Enzyme reactions

• Enzyme class: E.C.3.1.4.- - ?????