PDBsum entry 3v64

Protein binding

PDB id: 3v64

Contents

Protein chains

338 a.a.

191 a.a.

Ligands

NAG ×2

PO4 ×4

Metals

_CA ×5

Waters ×110

PDB id:

3v64

Name:

Protein binding

Title:

Crystal structure of agrin and lrp4

Structure:

Low-density lipoprotein receptor-related protein 4. Chain: c, d. Fragment: lg3 domain (unp residues 1759-1948). Synonym: lrp-4,multiple epidermal growth factor-like domains 7. Engineered: yes. Isoform 4 of agrin. Chain: a, b. Fragment: beta 1 propeller (unp residues 396-737). Engineered: yes

Source:

Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: lrp4, megf7. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: agrn, agrin. Expression_system_taxid: 7108

Resolution:

2.85Å R-factor: 0.206 R-free: 0.273

Authors:

Y.Zong,B.Zhang,S.Gu,K.Lee,J.Zhou,G.Yao,D.Figueiedo,K.Perry,L.Mei, R.Jin

Key ref:

Y.Zong et al. (2012). Structural basis of agrin-LRP4-MuSK signaling. Genes Dev, 26, 247-258. PubMed id: 22302937

Date:

18-Dec-11 Release date: 25-Apr-12

Protein chains

Q9QYP1  (LRP4_RAT) -  Low-density lipoprotein receptor-related protein 4 from Rattus norvegicus

Seq: 1905 a.a.

Struc: 338 a.a.*

Protein chains

P25304  (AGRIN_RAT) -  Agrin from Rattus norvegicus

Seq: 1959 a.a.

Struc: 191 a.a.*

* PDB and UniProt seqs differ at 8 residue positions (black crosses)

Genes Dev 26:247-258 (2012)

PubMed id: 22302937

Structural basis of agrin-LRP4-MuSK signaling.

Y.Zong, B.Zhang, S.Gu, K.Lee, J.Zhou, G.Yao, D.Figueiredo, K.Perry, L.Mei, R.Jin.

ABSTRACT

No abstract given.