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PDBsum entry 3v47
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Immune system
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PDB id
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3v47
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PDB id:
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Immune system
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Title:
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Crystal structure of the n-terminal fragment of zebrafish tlr5 in complex with salmonella flagellin
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Structure:
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Toll-like receptor 5b and variable lymphocyte receptor b.61 chimeric protein. Chain: a, b. Fragment: zebrafish toll-like receptor 5b (unp residues 22-390), hagfish variable lymphocyte receptor b.61 (unp residues 126-200). Engineered: yes. Mutation: yes. Flagellin. Chain: c, d.
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Source:
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Danio rerio, eptatretus burgeri. Zebra fish, inshore hagfish. Organism_taxid: 7955, 7764. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: hi5. Salmonella enterica subsp. Enterica serovar dublin. Organism_taxid: 98360.
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Resolution:
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2.47Å
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R-factor:
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0.223
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R-free:
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0.259
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Authors:
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S.I.Yoon,H.Hong,I.A.Wilson
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Key ref:
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S.I.Yoon
et al.
(2012).
Structural basis of TLR5-flagellin recognition and signaling.
Science,
335,
859-864.
PubMed id:
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Date:
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14-Dec-11
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Release date:
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29-Feb-12
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PROCHECK
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Headers
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References
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B3DIN1
(B3DIN1_DANRE) -
Tlr5b protein from Danio rerio
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Seq:
Struc:
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875 a.a.
441 a.a.*
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Science
335:859-864
(2012)
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PubMed id:
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Structural basis of TLR5-flagellin recognition and signaling.
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S.I.Yoon,
O.Kurnasov,
V.Natarajan,
M.Hong,
A.V.Gudkov,
A.L.Osterman,
I.A.Wilson.
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ABSTRACT
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Links
