 |
PDBsum entry 3ux9
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cytokine/immune system
|
PDB id
|
|
|
|
3ux9
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Cytokine/immune system
|
|
|
Title:
|
|
Structural insights into a human anti-ifn antibody exerting therapeutic potential for systemic lupus erythematosus
|
|
Structure:
|
|
Interferon alpha-1/13. Chain: a, c. Synonym: interferon 1b, ifn-alpha-1/13, interferon alpha-d, leif d. Engineered: yes. Scfv antibody. Chain: b, d. Engineered: yes
|
|
Source:
|
|
Homo sapiens. Human. Organism_taxid: 9606. Gene: ifna1, ifna13. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
Resolution:
|
|
|
2.80Å
|
R-factor:
|
0.186
|
R-free:
|
0.243
|
|
|
Authors:
|
|
S.Ouyang,L.X.Zhao,W.Liang,N.Shaw,Z.-J.Liu,M.-F.Liang
|
|
Key ref:
|
|
S.Ouyang
et al.
(2012).
Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus.
J Mol Med (berl),
90,
837-846.
PubMed id:
|
|
|
Date:
|
|
|
04-Dec-11
|
Release date:
|
29-Feb-12
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
| |
|
|
J Mol Med (berl)
90:837-846
(2012)
|
|
PubMed id:
|
|
|
|
|
|
| |
|
Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus.
|
|
S.Ouyang,
B.Gong,
J.Z.Li,
L.X.Zhao,
W.Wu,
F.S.Zhang,
L.Sun,
S.J.Wang,
M.Pan,
C.Li,
W.Liang,
N.Shaw,
J.Zheng,
G.P.Zhao,
Y.Wang,
Z.J.Liu,
M.Liang.
|
|
|
|
|
| |
ABSTRACT
|
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
 |
 |
|
|
Links
