PDBsum entry 3uvu

Protein binding/peptide

PDB id: 3uvu

Contents

Protein chains

19 a.a.

425 a.a.

Waters ×157

PDB id:

3uvu

Name:

Protein binding/peptide

Title:

Structural basis of nuclear import of flap endonuclease 1 (fen1)

Structure:

Flap endonuclease 1 (fen1) peptide. Chain: b. Synonym: fen-1, dnase iv, flap structure-specific endonuclease 1, maturation factor 1, mf1, hfen-1. Engineered: yes. Importin subunit alpha-2. Chain: a. Engineered: yes

Source:

Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Mus musculus. Mouse. Organism_taxid: 10090. Gene: kpna2, rch1. Expressed in: escherichia coli.

Resolution:

2.38Å R-factor: 0.170 R-free: 0.215

Authors:

A.C.Barros,A.A.S.Takeda,M.R.M.Fontes

Key ref:

A.C.de Barros et al. (2012). Structural basis of nuclear import of flap endonuclease 1 (FEN1). Acta Crystallogr D Biol Crystallogr, 68, 743-750. PubMed id: 22751659

Date:

30-Nov-11 Release date: 27-Jun-12

Protein chain

P39748  (FEN1_HUMAN) -  Flap endonuclease 1 from Homo sapiens

Seq: 380 a.a.

Struc: 19 a.a.

Protein chain

P52293  (IMA1_MOUSE) -  Importin subunit alpha-1 from Mus musculus

Seq: 529 a.a.

Struc: 425 a.a.

Enzyme reactions

• Enzyme class: Chain B: E.C.3.1.-.-

Acta Crystallogr D Biol Crystallogr 68:743-750 (2012)

PubMed id: 22751659

Structural basis of nuclear import of flap endonuclease 1 (FEN1).

A.C.de Barros, A.A.Takeda, C.W.Chang, B.Kobe, M.R.Fontes.

ABSTRACT

No abstract given.