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PDBsum entry 3uvu

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protein Protein-protein interface(s) links
Protein binding/peptide PDB id
3uvu
Jmol PyMol
Contents
Protein chains
19 a.a.
425 a.a.
Waters ×157
PDB id:
3uvu
Name: Protein binding/peptide
Title: Structural basis of nuclear import of flap endonuclease 1 (f
Structure: Flap endonuclease 1 (fen1) peptide. Chain: b. Synonym: fen-1, dnase iv, flap structure-specific endonucle maturation factor 1, mf1, hfen-1. Engineered: yes. Importin subunit alpha-2. Chain: a. Engineered: yes
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Mus musculus. Mouse. Organism_taxid: 10090. Gene: kpna2, rch1. Expressed in: escherichia coli.
Resolution:
2.38Å     R-factor:   0.170     R-free:   0.215
Authors: A.C.Barros,A.A.S.Takeda,M.R.M.Fontes
Key ref: A.C.de Barros et al. (2012). Structural basis of nuclear import of flap endonuclease 1 (FEN1). Acta Crystallogr D Biol Crystallogr, 68, 743-750. PubMed id: 22751659 DOI: 10.1107/S0907444912010281
Date:
30-Nov-11     Release date:   27-Jun-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P39748  (FEN1_HUMAN) -  Flap endonuclease 1
Seq:
Struc:
380 a.a.
19 a.a.
Protein chain
Pfam   ArchSchema ?
P52293  (IMA2_MOUSE) -  Importin subunit alpha-1
Seq:
Struc:
 
Seq:
Struc:
529 a.a.
425 a.a.
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     cytoplasm   3 terms 
  Biological process     protein import into nucleus   2 terms 
  Biochemical function     protein transporter activity     2 terms  

 

 
DOI no: 10.1107/S0907444912010281 Acta Crystallogr D Biol Crystallogr 68:743-750 (2012)
PubMed id: 22751659  
 
 
Structural basis of nuclear import of flap endonuclease 1 (FEN1).
A.C.de Barros, A.A.Takeda, C.W.Chang, B.Kobe, M.R.Fontes.
 
  ABSTRACT  
 
No abstract given.

 

 

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