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PDBsum entry 3uv2

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Transcription PDB id
3uv2

 

 

 

 

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Contents
Protein chain
119 a.a.
Ligands
7PE
Waters ×204
PDB id:
3uv2
Name: Transcription
Title: Crystal structure of the bromodomain of human nucleosome-remodeling factor subunit bptf
Structure: Bromodomain of human nucleosome-remodeling factor subunit bptf. Chain: a. Fragment: unp residues 2914-3037. Synonym: bromodomain and phd finger-containing transcription factor. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: bptf, fac1, falz. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.58Å     R-factor:   0.165     R-free:   0.209
Authors: P.Filippakopoulos,S.Picaud,T.Keates,E.Ugochukwu,F.Von Delft, C.H.Arrowsmith,A.M.Edwards,J.Weigelt,C.Bountra,S.Knapp,Structural Genomics Consortium (Sgc)
Key ref: P.Filippakopoulos et al. (2012). Histone recognition and large-scale structural analysis of the human bromodomain family. Cell, 149, 214-231. PubMed id: 22464331
Date:
29-Nov-11     Release date:   18-Jan-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q12830  (BPTF_HUMAN) -  Nucleosome-remodeling factor subunit BPTF from Homo sapiens
Seq:
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Seq:
Struc:
3046 a.a.
119 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
Cell 149:214-231 (2012)
PubMed id: 22464331  
 
 
Histone recognition and large-scale structural analysis of the human bromodomain family.
P.Filippakopoulos, S.Picaud, M.Mangos, T.Keates, J.P.Lambert, D.Barsyte-Lovejoy, I.Felletar, R.Volkmer, S.Müller, T.Pawson, A.C.Gingras, C.H.Arrowsmith, S.Knapp.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23211769 C.A.Musselman, M.E.Lalonde, J.Côté, and T.G.Kutateladze (2012).
Perceiving the epigenetic landscape through histone readers.
  Nat Struct Mol Biol, 19, 1218-1227.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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