PDBsum entry 3utz

Immune system

PDB id: 3utz

Contents

Protein chains

215 a.a.

217 a.a.

Ligands

SO4 ×10

Waters ×5

PDB id:

3utz

Name:

Immune system

Title:

Endogenous-like inhibitory antibodies targeting activated metalloproteinase motifs show therapeutic potential

Structure:

Metalloproteinase, light chain. Chain: a, d, e. Engineered: yes. Metalloproteinase, heavy chain. Chain: b, c, f. Engineered: yes

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562

Resolution:

2.18Å R-factor: 0.231 R-free: 0.288

Authors:

N.Sela-Passwell,R.Kikkeri,O.Dym,H.Rozenberg,R.Margalit,R.Arad-Yellin, M.Eisenstein,O.Brenner,T.Shoham,T.Danon,A.Shanzer,I.Sagi,Israel Structural Proteomics Center (Ispc)

Key ref:

N.Sela-Passwell et al. (2011). Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential. Nat Med, 18, 143-147. PubMed id: 22198278

Date:

27-Nov-11 Release date: 14-Dec-11

Protein chains

No UniProt id for this chain

Struc: 215 a.a.

Protein chains

No UniProt id for this chain

Struc: 217 a.a.

Nat Med 18:143-147 (2011)

PubMed id: 22198278

Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential.

N.Sela-Passwell, R.Kikkeri, O.Dym, H.Rozenberg, R.Margalit, R.Arad-Yellin, M.Eisenstein, O.Brenner, T.Shoham, T.Danon, A.Shanzer, I.Sagi.

ABSTRACT

No abstract given.