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PDBsum entry 3ulu

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protein ligands Protein-protein interface(s) links
Immune system PDB id
3ulu

 

 

 

 

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Contents
Protein chains
659 a.a.
214 a.a.
225 a.a.
210 a.a.
224 a.a.
215 a.a.
217 a.a.
Ligands
NAG-NAG ×4
NAG-NAG-BMA-MAN
NAG-NAG-BMA
NAG ×5
SO4
PDB id:
3ulu
Name: Immune system
Title: Structure of quaternary complex of human tlr3ecd with three fabs (form1)
Structure: Toll-like receptor 3. Chain: a. Fragment: unp residues 22-702. Synonym: tlr3ecd. Engineered: yes. Fab15 light chain. Chain: l. Engineered: yes. Fab15 heavy chain.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tlr3. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293.
Resolution:
3.52Å     R-factor:   0.270     R-free:   0.309
Authors: J.Luo,G.L.Gilliland,O.Obmolova,T.Malia,A.Teplyakov
Key ref: J.Luo et al. (2012). Lateral clustering of TLR3:dsRNA signaling units revealed by TLR3ecd:3Fabs quaternary structure. J Mol Biol, 421, 112-124. PubMed id: 22579623
Date:
11-Nov-11     Release date:   23-May-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
O15455  (TLR3_HUMAN) -  Toll-like receptor 3 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
904 a.a.
659 a.a.
Protein chain
No UniProt id for this chain
Struc: 214 a.a.
Protein chain
No UniProt id for this chain
Struc: 225 a.a.
Protein chain
No UniProt id for this chain
Struc: 210 a.a.
Protein chain
No UniProt id for this chain
Struc: 224 a.a.
Protein chain
No UniProt id for this chain
Struc: 215 a.a.
Protein chain
No UniProt id for this chain
Struc: 217 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 

 
J Mol Biol 421:112-124 (2012)
PubMed id: 22579623  
 
 
Lateral clustering of TLR3:dsRNA signaling units revealed by TLR3ecd:3Fabs quaternary structure.
J.Luo, G.Obmolova, T.J.Malia, S.J.Wu, K.E.Duffy, J.D.Marion, J.K.Bell, P.Ge, Z.H.Zhou, A.Teplyakov, Y.Zhao, R.J.Lamb, J.L.Jordan, L.R.San Mateo, R.W.Sweet, G.L.Gilliland.
 
  ABSTRACT  
 
No abstract given.

 

 

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