PDBsum entry 3ul0

Protein transport/protein binding

PDB id: 3ul0

Contents

Protein chains

426 a.a.

23 a.a.

Waters ×330

PDB id:

3ul0

Name:

Protein transport/protein binding

Title:

Mouse importin alpha: mouse cbp80y8d cnls complex

Structure:

Importin subunit alpha-2. Chain: b. Fragment: unp residues 70-529. Synonym: importin alpha p1, karyopherin subunit alpha-2, pendulin, pore targeting complex 58 kda subunit, ptac58, rag cohort protein 1, srp1-alpha. Engineered: yes. Nuclear cap-binding protein subunit 1. Chain: c.

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: kpna2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cbp80. Expression_system_taxid: 562

Resolution:

2.00Å R-factor: 0.189 R-free: 0.208

Authors:

M.Marfori,J.K.Forwood,T.G.Lonhienne,B.Kobe

Key ref:

M.Marfori et al. (2012). Structural basis of high-affinity nuclear localization signal interactions with importin-α. Traffic, 13, 532-548. PubMed id: 22248489

Date:

10-Nov-11 Release date: 03-Oct-12

Protein chain

P52293  (IMA1_MOUSE) -  Importin subunit alpha-1 from Mus musculus

Seq: 529 a.a.

Struc: 426 a.a.

Protein chain

Q3UYV9  (NCBP1_MOUSE) -  Nuclear cap-binding protein subunit 1 from Mus musculus

Seq: 790 a.a.

Struc: 23 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Traffic 13:532-548 (2012)

PubMed id: 22248489

Structural basis of high-affinity nuclear localization signal interactions with importin-α.

M.Marfori, T.G.Lonhienne, J.K.Forwood, B.Kobe.

ABSTRACT

No abstract given.