PDBsum entry 3ukw

Protein transport/inhibitor

PDB id: 3ukw

Contents

Protein chains

426 a.a.

22 a.a.

Ligands

BTB

Waters ×276

PDB id:

3ukw

Name:

Protein transport/inhibitor

Title:

Mouse importin alpha: bimax1 peptide complex

Structure:

Importin subunit alpha-2. Chain: b. Fragment: unp residues 70-529. Synonym: importin alpha p1, karyopherin subunit alpha-2, pendulin, pore targeting complex 58 kda subunit, ptac58, rag cohort protein 1, srp1-alpha. Engineered: yes. Bimax1 peptide. Chain: c.

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: kpna2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: designed peptide inhibitor

Resolution:

2.10Å R-factor: 0.178 R-free: 0.200

Authors:

M.Marfori,J.K.Forwood,T.G.Lonhienne,B.Kobe

Key ref:

M.Marfori et al. (2012). Structural basis of high-affinity nuclear localization signal interactions with importin-α. Traffic, 13, 532-548. PubMed id: 22248489

Date:

10-Nov-11 Release date: 03-Oct-12

Protein chain

P52293  (IMA1_MOUSE) -  Importin subunit alpha-1 from Mus musculus

Seq: 529 a.a.

Struc: 426 a.a.

Protein chain

No UniProt id for this chain

Struc: 22 a.a.

Traffic 13:532-548 (2012)

PubMed id: 22248489

Structural basis of high-affinity nuclear localization signal interactions with importin-α.

M.Marfori, T.G.Lonhienne, J.K.Forwood, B.Kobe.

ABSTRACT

No abstract given.