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PDBsum entry 3ucr
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Signaling protein
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PDB id
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3ucr
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PDB id:
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Signaling protein
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Title:
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Crystal structure of the immunoreceptor tigit igv domain
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Structure:
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T cell immunoreceptor with ig and itim domains. Chain: a, b, c, d. Fragment: unp residues 23-128. Synonym: v-set and immunoglobulin domain-containing protein 9, v-set and transmembrane domain-containing protein 3. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: tigit, vsig9, vstm3. Expressed in: escherichia coli. Expression_system_taxid: 562
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Resolution:
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2.63Å
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R-factor:
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0.218
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R-free:
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0.274
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Authors:
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J.P.Yin,K.F.Stengel,L.Rouge,J.F.Bazan,C.Wiesmann
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Key ref:
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K.F.Stengel
et al.
(2012).
Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.
Proc Natl Acad Sci U S A,
109,
5399-5404.
PubMed id:
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Date:
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27-Oct-11
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Release date:
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14-Mar-12
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PROCHECK
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Headers
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References
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Q495A1
(TIGIT_HUMAN) -
T-cell immunoreceptor with Ig and ITIM domains from Homo sapiens
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Seq:
Struc:
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244 a.a.
106 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Proc Natl Acad Sci U S A
109:5399-5404
(2012)
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PubMed id:
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Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.
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K.F.Stengel,
K.Harden-Bowles,
X.Yu,
L.Rouge,
J.Yin,
L.Comps-Agrar,
C.Wiesmann,
J.F.Bazan,
D.L.Eaton,
J.L.Grogan.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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O.J.Harrison,
J.Vendome,
J.Brasch,
X.Jin,
S.Hong,
P.S.Katsamba,
G.Ahlsen,
R.B.Troyanovsky,
S.M.Troyanovsky,
B.Honig,
and
L.Shapiro
(2012).
Nectin ectodomain structures reveal a canonical adhesive interface.
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Nat Struct Mol Biol,
19,
906-915.
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PDB codes:
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
codes are
shown on the right.
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Links
