| UniProt functional annotation for Q39193 | |||
| UniProt code: Q39193. |
| Organism: | Arabidopsis thaliana (Mouse-ear cress). | |
| Taxonomy: | Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. | |
| Function: | Together with SRK2D, key component and activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as seed germination, Pro accumulation, root growth inhibition, dormancy and seedling growth, and, to a lesser extent, stomatal closure. {ECO:0000269|PubMed:17307925}. | |
| Catalytic activity: | Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA- COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1; | |
| Catalytic activity: | Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.1; | |
| Activity regulation: | Activated by autophosphorylation of its activation loop. {ECO:0000269|PubMed:22160701}. | |
| Subunit: | Interacts with ABI1 (PubMed:19874541). Interacts with I-2 and TOPP1 (PubMed:26943172). {ECO:0000269|PubMed:19874541, ECO:0000269|PubMed:26943172}. | |
| Tissue specificity: | Expressed at low levels in seeds, seedlings, roots (especially in tips), stems, leaves, shoots, flowers and siliques. {ECO:0000269|PubMed:15292193, ECO:0000269|PubMed:17307925}. | |
| Induction: | By abscisic acid (ABA), salt, and osmotic stress (at protein level). {ECO:0000269|PubMed:15292193, ECO:0000269|PubMed:16365038}. | |
| Ptm: | Autophosphorylated in vitro. {ECO:0000269|PubMed:22160701}. | |
| Similarity: | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}. | |
| Sequence caution: | Sequence=AAM13097.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; | |
Annotations taken from UniProtKB at the EBI.