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UniProt functional annotation for P04525 | ||
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| UniProt code: P04525. |
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| Organism: | |
Enterobacteria phage T4 (Bacteriophage T4). |
| Taxonomy: | |
Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus. |
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| Function: | |
Replisome processivity clamp subunit that increases the processivity of DNA synthesis. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. {ECO:0000269|PubMed:10535942}. |
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| Subunit: | |
Homotrimer (PubMed:26735934). Part of the replicase complex that includes the DNA polymerase, the polymerase clamp, the clamp loader complex, the single-stranded DNA binding protein, the primase, the helicase and the helicase assembly factor (PubMed:16800624, PubMed:26102578). Interacts with the DNA polymerase; this interaction constitutes the polymerase holoenzyme (PubMed:8475061). {ECO:0000269|PubMed:16800624, ECO:0000269|PubMed:26102578, ECO:0000269|PubMed:26735934, ECO:0000269|PubMed:8475061}. |
| Similarity: | |
Belongs to the tevenvirinae DNA polymerase processivity component family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.