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PDBsum entry 3u5z
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protein dna_rna ligands metals Protein-protein interface(s) links
DNA binding protein/DNA PDB id
3u5z

 

 

 

 

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Contents
Protein chains
(+ 2 more) 320 a.a.
186 a.a.
(+ 0 more) 228 a.a.
DNA/RNA
Ligands
08T ×6
ADP ×2
Metals
_MG ×8
PDB id:
3u5z
Name: DNA binding protein/DNA
Title: Structure of t4 bacteriophage clamp loader bound to the t4 clamp, primer-template DNA, and atp analog
Structure: DNA polymerase accessory protein 44. Chain: b, c, d, e, l, m, n, o. Synonym: clamp loader large subunit, protein gp44. Engineered: yes. DNA polymerase accessory protein 62. Chain: a, k. Synonym: clamp loader small subunit, protein gp62. Engineered: yes. DNA polymerase processivity component.
Source: Enterobacteria phage t4. Organism_taxid: 10665. Gene: 44, gp44. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: 62, gp62. Gene: 45, gp45. Synthetic: yes. Synthetic: yes
Resolution:
3.50Å     R-factor:   0.232     R-free:   0.279
Authors: B.A.Kelch,D.L.Makino,M.O'Donnell,J.Kuriyan
Key ref: B.A.Kelch et al. (2011). How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 1675-1680. PubMed id: 22194570
Date:
11-Oct-11     Release date:   04-Jan-12    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P04526  (DPA44_BPT4) -  Sliding-clamp-loader large subunit from Enterobacteria phage T4
Seq:
Struc: 		319 a.a.
320 a.a.
Protein chains
Pfam   ArchSchema ?
P04527  (DPA62_BPT4) -  Sliding-clamp-loader small subunit from Enterobacteria phage T4
Seq:
Struc: 		187 a.a.
186 a.a.
Protein chains
Pfam   ArchSchema ?
P04525  (DPA5_BPT4) -  Sliding clamp from Enterobacteria phage T4
Seq:
Struc: 		228 a.a.
228 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

DNA/RNA chains
  T-T-T-T-T-A-T-G-T-A-C-T-C-G-T-A-G-T-G-T-C-T-G-C 24 bases
  G-C-A-G-A-C-A-C-T-A-C-G-A-G-T-A-C-A-T-A 20 bases
  T-T-T-T-T-A-T-G-T-A-C-T-C-G-T-A-G-T-G-T-C-T-G-C 24 bases
  G-C-A-G-A-C-A-C-T-A-C-G-A-G-T-A-C-A-T-A 20 bases

 Enzyme reactions 
   Enzyme class: Chains B, C, D, E, L, M, N, O: E.C.3.6.4.-  - ?????
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
Science 334:1675-1680 (2011)
PubMed id: 22194570  
 
 
How a DNA polymerase clamp loader opens a sliding clamp.
B.A.Kelch, D.L.Makino, M.O'Donnell, J.Kuriyan.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
22382979 A.A.Armstrong, F.Mohideen, and C.D.Lima (2012).
Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.
  Nature, 483, 59-63.
PDB codes: 3v60 3v61 3v62
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB codes are shown on the right.

 

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