PDBsum entry 3u5v

Transcription

PDB id

3u5v

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Contents

			Protein chain

					62 a.a.

			Ligands

					NO3 ×2

			Waters ×34

PDB id:

3u5v

Links

Name:

Transcription

Title:

Crystal structure of max-e47

Structure:

Protein max, transcription factor e2-alpha chimera. Chain: a. Fragment: see remark 999. Synonym: myc-associated factor x, myc-binding novel hlh/lz protein, protein myn, immunoglobulin enhancer-binding factor e47, class b basic helix-loop-helix protein 21, bhlhb21, immunoglobulin transcription factor 1, kappa-e2-binding factor, transcription factor 3, tcf-3, transcription factor itf-1. Engineered: yes

Source:

Mus musculus, homo sapiens. Mouse, human. Organism_taxid: 10090, 9606. Gene: max, myn, bhlhb21, e2a, itf1, tcf3. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.70Å

R-factor:

0.208

R-free:

0.235

Authors:

A.Guarne,F.Ahmadpour,M.Gloyd

Key ref:

F.Ahmadpour et al. (2012). Crystal structure of the minimalist Max-E47 protein chimera. Plos One, 7, e32136. PubMed id: 22389683

Date:

11-Oct-11

Release date:

21-Mar-12

PROCHECK

	Headers

	References

Protein chain

P15923 (TFE2_HUMAN) - Transcription factor E2-alpha from Homo sapiens

Seq: Struc:

Seq: Struc:					654 a.a. 62 a.a.*

Protein chain

P28574 (MAX_MOUSE) - Protein max from Mus musculus

Seq: Struc:					160 a.a. 62 a.a.*

Key:

Secondary structure

CATH domain

* PDB and UniProt seqs differ at 53 residue positions (black crosses)

	Plos One 7:e32136 (2012)
PubMed id: 22389683

Crystal structure of the minimalist Max-E47 protein chimera.
F.Ahmadpour, R.Ghirlando, A.T.De Jong, M.Gloyd, J.A.Shin, A.Guarné.

ABSTRACT

No abstract given.

Literature references that cite this PDB file's key reference

PubMed id

Reference

23143595

J.Richter, M.Schlesner, S.Hoffmann, M.Kreuz, E.Leich, B.Burkhardt, M.Rosolowski, O.Ammerpohl, R.Wagener, S.H.Bernhart, D.Lenze, M.Szczepanowski, M.Paulsen, S.Lipinski, R.B.Russell, S.Adam-Klages, G.Apic, A.Claviez, D.Hasenclever, V.Hovestadt, N.Hornig, J.O.Korbel, D.Kube, D.Langenberger, C.Lawerenz, J.Lisfeld, K.Meyer, S.Picelli, J.Pischimarov, B.Radlwimmer, T.Rausch, M.Rohde, M.Schilhabel, R.Scholtysik, R.Spang, H.Trautmann, T.Zenz, A.Borkhardt, H.G.Drexler, P.Möller, R.A.Macleod, C.Pott, S.Schreiber, L.Trümper, M.Loeffler, P.F.Stadler, P.Lichter, R.Eils, R.Küppers, M.Hummel, W.Klapper, P.Rosenstiel, A.Rosenwald, B.Brors, and R.Siebert (2012).
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing.

Nat Genet, 44, 1316-1320.

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