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PDBsum entry 3u5o
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Transcription
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PDB id
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3u5o
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Contents |
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(+ 2 more)
189 a.a.
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(+ 2 more)
20 a.a.
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PDB id:
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| Name: |
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Transcription
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Title:
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Crystal structure of the complex of trim33 phd-bromo and h3(1-22) k9me3k14ack18ac histone peptide
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Structure:
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E3 ubiquitin-protein ligase trim33. Chain: a, b, c, d, e, f, g, h. Fragment: the phd and bromo domain of trim33. Synonym: ectodermin homolog, ret-fused gene 7 protein, protein rfg7, transcription intermediary factor 1-gamma, tif1-gamma, tripartite motif-containing protein 33. Engineered: yes. Histone h3.1. Chain: i, j, k, l, m, n, o, p.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: trim33, kiaa1113, rfg7, tif1g. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: this sequence occurs naturally in humans
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Resolution:
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2.70Å
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R-factor:
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0.207
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R-free:
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0.280
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Authors:
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Z.Wang,D.J.Patel
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Key ref:
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Q.Xi
et al.
(2011).
A poised chromatin platform for TGF-β access to master regulators.
Cell,
147,
1511-1524.
PubMed id:
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Date:
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11-Oct-11
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Release date:
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18-Jan-12
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PROCHECK
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Headers
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References
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Enzyme class 2:
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Chains A, B, C, D, E, F, G, H:
E.C.2.3.2.27
- RING-type E3 ubiquitin transferase.
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Reaction:
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S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6- ubiquitinyl-[acceptor protein]-L-lysine
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Enzyme class 3:
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Chains I, J, K, L, M, N, O, P:
E.C.?
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Note, where more than one E.C. class is given (as above), each may
correspond to a different protein domain or, in the case of polyprotein
precursors, to a different mature protein.
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Cell
147:1511-1524
(2011)
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PubMed id:
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A poised chromatin platform for TGF-β access to master regulators.
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Q.Xi,
Z.Wang,
A.I.Zaromytidou,
X.H.Zhang,
L.F.Chow-Tsang,
J.X.Liu,
H.Kim,
A.Barlas,
K.Manova-Todorova,
V.Kaartinen,
L.Studer,
W.Mark,
D.J.Patel,
J.Massagué.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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C.A.Musselman,
M.E.Lalonde,
J.Côté,
and
T.G.Kutateladze
(2012).
Perceiving the epigenetic landscape through histone readers.
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Nat Struct Mol Biol,
19,
1218-1227.
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J.Massagué
(2012).
TGFβ signalling in context.
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Nat Rev Mol Cell Biol,
13,
616-630.
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K.Aggarwal,
and
J.Massagué
(2012).
Ubiquitin removal in the TGF-β pathway.
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Nat Cell Biol,
14,
656-657.
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
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Links
