PDBsum entry 3tvt

Antitumor protein/protein binding

PDB id: 3tvt

Contents

Protein chains

255 a.a.

14 a.a.

Waters ×234

PDB id:

3tvt

Name:

Antitumor protein/protein binding

Title:

Structural basis for discs large interaction with pins

Structure:

Disks large 1 tumor suppressor protein. Chain: a. Fragment: see remark 999. Engineered: yes. Partner of inscuteable. Chain: b. Fragment: linker domain (unp residues 411-460). Synonym: pins. Engineered: yes.

Source:

Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: dlg1, l(1)dlg1, cg1725. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: raps, pins, cg5692.

Resolution:

1.60Å R-factor: 0.221 R-free: 0.245

Authors:

C.A.Johnston,C.Q.Doe,K.E.Prehoda

Key ref:

C.A.Johnston et al. Structural basis for discs large interaction with pin. To be published, .

Date:

20-Sep-11 Release date: 08-Aug-12

Protein chain

P31007  (DLG1_DROME) -  Disks large 1 tumor suppressor protein from Drosophila melanogaster

Seq: 970 a.a.

Struc: 255 a.a.

Protein chain

Q9VB22  (Q9VB22_DROME) -  LD33695p from Drosophila melanogaster

Seq: 658 a.a.

Struc: 14 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)