PDBsum entry 3tnu

Cytosolic protein

PDB id: 3tnu

Contents

Protein chains

90 a.a.

95 a.a.

Waters ×6

PDB id:

3tnu

Name:

Cytosolic protein

Title:

Heterocomplex of coil 2b domains of human intermediate filament proteins, keratin 5 (krt5) and keratin 14 (krt14)

Structure:

Keratin, type i cytoskeletal 14. Chain: a. Fragment: unp residues 295-422. Synonym: cytokeratin-14, ck-14, keratin-14, k14. Engineered: yes. Keratin, type ii cytoskeletal 5. Chain: b. Fragment: unp residues 350-477. Synonym: 58 kda cytokeratin, cytokeratin-5, ck-5, keratin-5, k5,

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: krt14. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: krt5. Expression_system_taxid: 562

Resolution:

3.01Å R-factor: 0.210 R-free: 0.234

Authors:

C.H.Lee,M.S.Kim,D.J.Leahy,P.A.Coulombe

Key ref:

C.H.Lee et al. (2012). Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. Nat Struct Biol, 19, 707-715. PubMed id: 22705788

Date:

02-Sep-11 Release date: 20-Jun-12

Protein chain

P02533  (K1C14_HUMAN) -  Keratin, type I cytoskeletal 14 from Homo sapiens

Seq: 472 a.a.

Struc: 90 a.a.

Protein chain

P13647  (K2C5_HUMAN) -  Keratin, type II cytoskeletal 5 from Homo sapiens

Seq: 590 a.a.

Struc: 95 a.a.

Nat Struct Biol 19:707-715 (2012)

PubMed id: 22705788

Structural basis for heteromeric assembly and perinuclear organization of keratin filaments.

C.H.Lee, M.S.Kim, B.M.Chung, D.J.Leahy, P.A.Coulombe.

ABSTRACT

No abstract given.