spacer
spacer

PDBsum entry 3tn0

Go to PDB code: 
protein ligands Protein-protein interface(s) links
Immune system PDB id
3tn0

 

 

 

 

Loading ...

 
JSmol PyMol  
Contents
Protein chains
293 a.a.
98 a.a.
203 a.a.
235 a.a.
Ligands
NAG-NAG
QUX
NAG ×2
PDB id:
3tn0
Name: Immune system
Title: Structure of mouse va14vb8.2nkt tcr-mouse cd1d-a-c-galactosylceramide complex
Structure: Antigen-presenting glycoprotein cd1d1. Chain: a. Fragment: unp residues 19-297. Engineered: yes. Beta-2 microglobulin. Chain: b. Fragment: unp residues 21-119. Engineered: yes. Mouse nkt valpha14 (mouse variable domain, human constant
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: cd1d1, cd1.1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Gene: b2m, rp23-34e24.5-001, mcg_11606. Homo sapiens, mus musculus. Organism_taxid: 9606, 10090.
Resolution:
3.20Å     R-factor:   0.229     R-free:   0.289
Authors: O.Patel,J.Rossjohn
Key ref: O.Patel et al. (2011). NKT TCR recognition of CD1d-α-C-galactosylceramide. J Immunol, 187, 4705-4713. PubMed id: 21964029
Date:
01-Sep-11     Release date:   14-Dec-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P11609  (CD1D1_MOUSE) -  Antigen-presenting glycoprotein CD1d1 from Mus musculus
Seq:
Struc:
336 a.a.
293 a.a.*
Protein chain
Pfam   ArchSchema ?
P01887  (B2MG_MOUSE) -  Beta-2-microglobulin from Mus musculus
Seq:
Struc:
119 a.a.
98 a.a.
Protein chain
Pfam   ArchSchema ?
P01848  (TCA_HUMAN) -  T cell receptor alpha chain constant from Homo sapiens
Seq:
Struc:
140 a.a.
203 a.a.*
Protein chain
Pfam   ArchSchema ?
P01850  (TRBC1_HUMAN) -  T cell receptor beta constant 1 from Homo sapiens
Seq:
Struc:
176 a.a.
235 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 27 residue positions (black crosses)

 

 
J Immunol 187:4705-4713 (2011)
PubMed id: 21964029  
 
 
NKT TCR recognition of CD1d-α-C-galactosylceramide.
O.Patel, G.Cameron, D.G.Pellicci, Z.Liu, H.S.Byun, T.Beddoe, J.McCluskey, R.W.Franck, A.R.Castaño, Y.Harrak, A.Llebaria, R.Bittman, S.A.Porcelli, D.I.Godfrey, J.Rossjohn.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23154222 J.Rossjohn, D.G.Pellicci, O.Patel, L.Gapin, and D.I.Godfrey (2012).
Recognition of CD1d-restricted antigens by natural killer T cells.
  Nat Rev Immunol, 12, 845-857.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

spacer

spacer