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PDBsum entry 3tje

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protein ligands metals Protein-protein interface(s) links
Immune system PDB id
3tje

 

 

 

 

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Contents
Protein chains
213 a.a.
229 a.a.
100 a.a.
Ligands
EDO ×5
Metals
_CL
_CD ×2
Waters ×395
PDB id:
3tje
Name: Immune system
Title: Crystal structure of fas receptor extracellular domain in complex with fab e09
Structure: Fab e09, light chain. Chain: l. Engineered: yes. Fab e09, heavy chain. Chain: h. Engineered: yes. Tumor necrosis factor receptor superfamily member 6. Chain: f. Synonym: apo-1 antigen, apoptosis-mediating surface antigen fas,
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell: hek ebna-293. Gene: apt1, fas, fas1, tnfrsf6. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
1.93Å     R-factor:   0.206     R-free:   0.232
Authors: S.Zuger,C.Stirnimann,C.Briand,M.G.Grutter
Key ref: M.Chodorge et al. (2012). A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency. Cell Death Differ, 19, 1187-1195. PubMed id: 22261618
Date:
24-Aug-11     Release date:   09-May-12    
PROCHECK
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 Headers
 References

Protein chain
No UniProt id for this chain
Struc: 213 a.a.
Protein chain
No UniProt id for this chain
Struc: 229 a.a.
Protein chain
Pfam   ArchSchema ?
P25445  (TNR6_HUMAN) -  Tumor necrosis factor receptor superfamily member 6 from Homo sapiens
Seq:
Struc:
335 a.a.
100 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 

 
Cell Death Differ 19:1187-1195 (2012)
PubMed id: 22261618  
 
 
A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
M.Chodorge, S.Züger, C.Stirnimann, C.Briand, L.Jermutus, M.G.Grütter, R.R.Minter.
 
  ABSTRACT  
 
No abstract given.

 

 

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