PDBsum entry 3tad

Protein binding

PDB id: 3tad

Contents

Protein chains

265 a.a.

252 a.a.

Ligands

GOL ×5

Waters ×13

PDB id:

3tad

Name:

Protein binding

Title:

Crystal structure of the liprin-alpha/liprin-beta complex

Structure:

Liprin-alpha-2. Chain: a, b. Fragment: unp residues 866-975, 1113-1193. Synonym: protein tyrosine phosphatase receptor type f polypeptide- interacting protein alpha-2, ptprf-interacting protein alpha-2. Engineered: yes. Liprin-beta-1. Chain: c, d. Fragment: unp residues 593-853.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ppfia2. Expressed in: escherichia coli. Expression_system_taxid: 562. Mus musculus. Mouse. Organism_taxid: 10090.

Resolution:

2.90Å R-factor: 0.216 R-free: 0.258

Authors:

Z.Wei,S.Zheng,C.Yu,M.Zhang

Key ref:

Z.Wei et al. (2011). Liprin-mediated large signaling complex organization revealed by the liprin-α/CASK and liprin-α/liprin-β complex structures. Mol Cell, 43, 586-598. PubMed id: 21855798

Date:

04-Aug-11 Release date: 12-Oct-11

Protein chains

O75334  (LIPA2_HUMAN) -  Liprin-alpha-2 from Homo sapiens

Seq: 1257 a.a.

Struc: 265 a.a.

Protein chains

Q8C8U0  (LIPB1_MOUSE) -  Liprin-beta-1 from Mus musculus

Seq: 969 a.a.

Struc: 252 a.a.

Enzyme reactions

• Enzyme class: Chains A, B, C, D: E.C.?

Mol Cell 43:586-598 (2011)

PubMed id: 21855798

Liprin-mediated large signaling complex organization revealed by the liprin-α/CASK and liprin-α/liprin-β complex structures.

Z.Wei, S.Zheng, S.A.Spangler, C.Yu, C.C.Hoogenraad, M.Zhang.

ABSTRACT

No abstract given.