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PDBsum entry 3t96
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Transport protein
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PDB id
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3t96
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PDB id:
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| Name: |
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Transport protein
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Title:
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Iodowillardiine bound to a double cysteine mutant (a452c/s652c) of the ligand binding domain of glua2
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Structure:
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Glutamate receptor 2. Chain: b, d, f. Fragment: see remark 999. Synonym: glua2, glur2, ampa-selective glutamate receptor 2, glur-b, glur-k2. Engineered: yes. Mutation: yes
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Source:
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Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: gria2,glua2. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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1.87Å
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R-factor:
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0.184
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R-free:
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0.219
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Authors:
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A.H.Ahmed,S.Wang,H.H.Chuang,R.E.Oswald
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Key ref:
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A.H.Ahmed
et al.
(2011).
Mechanism of AMPA receptor activation by partial agonists: disulfide trapping of closed lobe conformations.
J Biol Chem,
286,
35257-35266.
PubMed id:
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Date:
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02-Aug-11
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Release date:
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17-Aug-11
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PROCHECK
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Headers
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References
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P19491
(GRIA2_RAT) -
Glutamate receptor 2 from Rattus norvegicus
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Seq:
Struc:
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883 a.a.
258 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 4 residue positions (black
crosses)
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J Biol Chem
286:35257-35266
(2011)
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PubMed id:
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Mechanism of AMPA receptor activation by partial agonists: disulfide trapping of closed lobe conformations.
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A.H.Ahmed,
S.Wang,
H.H.Chuang,
R.E.Oswald.
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ABSTRACT
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Links
