PDBsum entry 3sl8

Hydrolase/hydrolase inhibitor

PDB id: 3sl8

Contents

Protein chains

327 a.a.

Ligands

EDO ×30

PEG ×2

JN7 ×4

PO4 ×2

DMS ×2

Metals

_ZN ×8

Waters ×236

References listed in PDB file

Key reference

• Title: Thiophene inhibitors of pde4: crystal structures show a second binding mode at the catalytic domain of pde4d2.
• Authors: J.L.Nankervis, S.C.Feil, N.C.Hancock, Z.Zheng, H.L.Ng, C.J.Morton, J.K.Holien, P.W.Ho, M.M.Frazzetto, I.G.Jennings, D.T.Manallack, T.J.Martin, P.E.Thompson, M.W.Parker.
• Ref.: Bioorg Med Chem Lett, 2011, 21, 7089-7093.
• PubMed id: 22030030

Abstract

No abstract given.