PDBsum entry 3skn

Immune system

PDB id: 3skn

Contents

Protein chains

197 a.a.

241 a.a.

PDB id:

3skn

Name:

Immune system

Title:

Crystal structure of the rl42 tcr unliganded

Structure:

Rl42 t cell receptor, alpha chain. Chain: a, c, e, g. Engineered: yes. Rl42 t cell receptor, beta chain. Chain: b, d, f, h. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.90Å R-factor: 0.199 R-free: 0.292

Authors:

S.Gras,P.G.Wilmann,C.Zhenjun,H.Hanim,L.Yu Chih,L.Kjer-Nielsen, A.W.Purcell,S.R.Burrows,J.Mccluskey,J.Rossjohn

Key ref:

S.Gras et al. (2012). A structural basis for varied αβ TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule. J Immunol, 188, 311-321. PubMed id: 22140258

Date:

22-Jun-11 Release date: 29-Feb-12

Protein chains

P01848  (TCA_HUMAN) -  T cell receptor alpha chain constant from Homo sapiens

Seq: 140 a.a.

Struc: 197 a.a.*

Protein chains

No UniProt id for this chain

Struc: 241 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)

J Immunol 188:311-321 (2012)

PubMed id: 22140258

A structural basis for varied αβ TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule.

S.Gras, P.G.Wilmann, Z.Chen, H.Halim, Y.C.Liu, L.Kjer-Nielsen, A.W.Purcell, S.R.Burrows, J.McCluskey, J.Rossjohn.

ABSTRACT

No abstract given.