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PDBsum entry 3se3
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Immune system receptor
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PDB id
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3se3
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Contents |
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285 a.a.
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128 a.a.
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183 a.a.
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PDB id:
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Immune system receptor
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Title:
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Human ifna2-ifnar ternary complex
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Structure:
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Interferon alpha/beta receptor 1. Chain: a. Fragment: ifna2(yns) (unp residues 28-436). Synonym: ifn-r-1, ifn-alpha/beta receptor 1, cytokine receptor class- ii member 1, cytokine receptor family 2 member 1, crf2-1, type i interferon receptor 1. Engineered: yes. Interferon alpha 2b. Chain: b.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: ifnar1, ifnar. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ifnar2, ifnabr, ifnarb.
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Resolution:
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4.00Å
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R-factor:
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0.251
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R-free:
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0.311
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Authors:
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C.Thomas,K.C.Garcia
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Key ref:
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C.Thomas
et al.
(2011).
Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell,
146,
621-632.
PubMed id:
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Date:
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10-Jun-11
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Release date:
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31-Aug-11
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PROCHECK
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Headers
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References
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P17181
(INAR1_HUMAN) -
Interferon alpha/beta receptor 1 from Homo sapiens
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Seq:
Struc:
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557 a.a.
285 a.a.
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Cell
146:621-632
(2011)
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PubMed id:
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Structural linkage between ligand discrimination and receptor activation by type I interferons.
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C.Thomas,
I.Moraga,
D.Levin,
P.O.Krutzik,
Y.Podoplelova,
A.Trejo,
C.Lee,
G.Yarden,
S.E.Vleck,
J.S.Glenn,
G.P.Nolan,
J.Piehler,
G.Schreiber,
K.C.Garcia.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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C.Thomas,
J.F.Bazan,
and
K.C.Garcia
(2012).
Structure of the activating IL-1 receptor signaling complex.
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Nat Struct Mol Biol,
19,
455-457.
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PDB code:
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
code is
shown on the right.
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Links
