PDBsum entry 3s4w

DNA binding protein

PDB id

3s4w

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Contents

			Protein chains

					1206 a.a.


					1146 a.a.

PDB id:

3s4w

Links

Name:

DNA binding protein

Title:

Structure of the fanci-fancd2 complex

Structure:

Fanconi anemia group i protein homolog. Chain: a. Synonym: protein faci. Engineered: yes. Fanconi anemia group d2 protein homolog. Chain: b. Fragment: unp residues 33-1415. Synonym: protein facd2. Engineered: yes

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: fanci. Gene: fancd2

Resolution:

3.41Å

R-factor:

0.241

R-free:

0.272

Authors:

N.P.Pavletich

Key ref:

W.Joo et al. (2011). Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway. Science, 333, 312-316. PubMed id: 21764741

Date:

20-May-11

Release date:

27-Jul-11

PROCHECK

	Headers

	References

Protein chain

Q8K368 (FANCI_MOUSE) - Fanconi anemia group I protein homolog from Mus musculus

Seq: Struc:

Seq: Struc:

Seq: Struc:					1330 a.a. 1206 a.a.

Protein chain

Q80V62 (FACD2_MOUSE) - Fanconi anemia group D2 protein homolog from Mus musculus

Seq: Struc:

Seq: Struc:

Seq: Struc:					1450 a.a. 1146 a.a.*

Key:

PfamA domain

Secondary structure

* PDB and UniProt seqs differ at 1 residue position (black cross)

	Science 333:312-316 (2011)
PubMed id: 21764741

Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.
W.Joo, G.Xu, N.S.Persky, A.Smogorzewska, D.G.Rudge, O.Buzovetsky, S.J.Elledge, N.P.Pavletich.

ABSTRACT

No abstract given.

Literature references that cite this PDB file's key reference

PubMed id

Reference

22266823

H.Kim, K.Yang, D.Dejsuphong, and A.D.D'Andrea (2012).
Regulation of Rev1 by the Fanconi anemia core complex.

Nat Struct Mol Biol, 19, 164-170.

The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.