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UniProt functional annotation for P35992 | ||
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| UniProt code: P35992. |
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| Organism: | |
Drosophila melanogaster (Fruit fly). |
| Taxonomy: | |
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. |
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| Function: | |
May have a role in axon outgrowth and guidance. {ECO:0000269|PubMed:1657401}. |
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| Catalytic activity: | |
Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136, Rhea:RHEA- COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:46858, ChEBI:CHEBI:82620; EC=3.1.3.48; Evidence={ECO:0000255|PROSITE- ProRule:PRU10044}; |
| Subcellular location: | |
Membrane; Single-pass type I membrane protein. |
| Tissue specificity: | |
In 9-12 hour embryos, expression is specifically seen in the anterior commissure and its junctions with the longitudinal tracts. {ECO:0000269|PubMed:1657401, ECO:0000269|PubMed:1657402}. |
| Developmental stage: | |
Expressed both maternally and zygotically. Expressed throughout development to adulthood, lowest expression is during second and third larval instars. {ECO:0000269|PubMed:1657401}. |
| Miscellaneous: | |
This protein is translated by readthrough of a stop codon. Readthrough of the terminator codon TAG occurs between the codons for Arg-1631 and His-1633. There is currently no sequence that provides the identity of residue 1632. {ECO:0000305}. |
| Similarity: | |
Belongs to the protein-tyrosine phosphatase family. Receptor class subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.