UniProt functional annotation for P35992

UniProt code: P35992.

Organism: Drosophila melanogaster (Fruit fly).
Taxonomy: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
 
Function: May have a role in axon outgrowth and guidance.
 
Catalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
Subcellular location: Membrane; Single-pass type I membrane protein.
Tissue specificity: In 9-12 hour embryos, expression is specifically seen in the anterior commissure and its junctions with the longitudinal tracts.
Developmental stage: Expressed both maternally and zygotically. Expressed throughout development to adulthood, lowest expression is during second and third larval instars.
Similarity: Belongs to the protein-tyrosine phosphatase family. Receptor class subfamily.
Similarity: Contains 12 fibronectin type-III domains.
Similarity: Contains 1 tyrosine-protein phosphatase domain.

Annotations taken from UniProtKB at the EBI.