PDBsum entry 3rzx

Protein transport

PDB id: 3rzx

Contents

Protein chains

427 a.a.

12 a.a.

Waters ×96

PDB id:

3rzx

Name:

Protein transport

Title:

Mouse importin alpha-ku70 nls peptide complex

Structure:

Importin subunit alpha-2. Chain: a. Fragment: nls binding domain. Synonym: importin alpha p1, karyopherin subunit alpha-2, pendulin, pore targeting complex 58 kda subunit, ptac58, rag cohort protein 1, srp1-alpha. Engineered: yes. Ku70 nls peptide. Chain: b.

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: kpna2, rch1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Homo sapiens. Human.

Resolution:

2.61Å R-factor: 0.170 R-free: 0.223

Authors:

A.A.S.Takeda,M.R.M.Fontes

Key ref:

A.A.Takeda et al. (2011). Structural basis of importin-α-mediated nuclear transport for Ku70 and Ku80. J Mol Biol, 412, 226-234. PubMed id: 21806995

Date:

12-May-11 Release date: 03-Aug-11

Protein chain

P52293  (IMA1_MOUSE) -  Importin subunit alpha-1 from Mus musculus

Seq: 529 a.a.

Struc: 427 a.a.

Protein chain

P12956  (XRCC6_HUMAN) -  X-ray repair cross-complementing protein 6 from Homo sapiens

Seq: 609 a.a.

Struc: 12 a.a.

Enzyme reactions

• Enzyme class 2: Chain B: E.C.3.6.4.- - ?????
• Enzyme class 3: Chain B: E.C.4.2.99.- - ?????

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

J Mol Biol 412:226-234 (2011)

PubMed id: 21806995

Structural basis of importin-α-mediated nuclear transport for Ku70 and Ku80.

A.A.Takeda, A.C.de Barros, C.W.Chang, B.Kobe, M.R.Fontes.

ABSTRACT

No abstract given.