PDBsum entry 3ry5

Immune system

PDB id: 3ry5

Contents

Protein chain

170 a.a.

Waters ×85

PDB id:

3ry5

Name:

Immune system

Title:

Three-dimensional structure of glycosylated fcgammariia (high- responder polymorphism)

Structure:

Low affinity immunoglobulin gamma fc region receptor ii-a. Chain: a. Fragment: extracellular domain, residues 114-327. Synonym: igg fc receptor ii-a, fc-gamma rii-a, fc-gamma-riia, fcrii- a, cdw32. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Tissue: blood. Gene: fcgr2a, cd32, fcg2, fcgr2a1, igfr2. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf21.

Resolution:

2.30Å R-factor: 0.206 R-free: 0.275

Authors:

P.A.Ramsland,W.Farrugia,P.M.Hogarth

Key ref:

P.A.Ramsland et al. (2011). Structural basis for Fc gammaRIIa recognition of human IgG and formation of inflammatory signaling complexes. J Immunol, 187, 3208-3217. PubMed id: 21856937

Date:

11-May-11 Release date: 31-Aug-11

Protein chain

P12318  (FCG2A_HUMAN) -  Low affinity immunoglobulin gamma Fc region receptor II-a from Homo sapiens

Seq: 317 a.a.

Struc: 170 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

J Immunol 187:3208-3217 (2011)

PubMed id: 21856937

Structural basis for Fc gammaRIIa recognition of human IgG and formation of inflammatory signaling complexes.

P.A.Ramsland, W.Farrugia, T.M.Bradford, C.T.Sardjono, S.Esparon, H.M.Trist, M.S.Powell, P.S.Tan, A.C.Cendron, B.D.Wines, A.M.Scott, P.M.Hogarth.

ABSTRACT

No abstract given.