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PDBsum entry 3rvx

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protein ligands metals Protein-protein interface(s) links
Hydrolase/immune system PDB id
3rvx

 

 

 

 

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Contents
Protein chains
222 a.a.
211 a.a.
214 a.a.
Ligands
EDO
Metals
_CA
Waters ×200
PDB id:
3rvx
Name: Hydrolase/immune system
Title: Crystal structure of der p 1 complexed with fab 4c1
Structure: Peptidase 1. Chain: a. Fragment: unp residues 99-320. Synonym: allergen der p i, major mite fecal allergen der p 1. 4c1 - light chain. Chain: c. Engineered: yes. 4c1 - heavy chain. Chain: d.
Source: Dermatophagoides pteronyssinus. European house dust mite. Organism_taxid: 6956. Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: mus musculus. Expression_system_taxid: 10090. Expression_system_cell_line: hybridoma.
Resolution:
2.50Å     R-factor:   0.180     R-free:   0.229
Authors: M.Chruszcz,L.D.Vailes,M.D.Chapman,A.Pomes,W.Minor
Key ref: M.Chruszcz et al. (2012). Molecular determinants for antibody binding on group 1 house dust mite allergens. J Biol Chem, 287, 7388-7398. PubMed id: 22210776
Date:
06-May-11     Release date:   11-Jan-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P08176  (PEPT1_DERPT) -  Peptidase 1 from Dermatophagoides pteronyssinus
Seq:
Struc:
320 a.a.
222 a.a.
Protein chain
No UniProt id for this chain
Struc: 211 a.a.
Protein chain
No UniProt id for this chain
Struc: 214 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: Chain A: E.C.3.4.22.65  - peptidase 1 (mite).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
J Biol Chem 287:7388-7398 (2012)
PubMed id: 22210776  
 
 
Molecular determinants for antibody binding on group 1 house dust mite allergens.
M.Chruszcz, A.Pomés, J.Glesner, L.D.Vailes, T.Osinski, P.J.Porebski, K.A.Majorek, P.W.Heymann, T.A.Platts-Mills, W.Minor, M.D.Chapman.
 
  ABSTRACT  
 
No abstract given.

 

 

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