UniProt functional annotation for P16311

UniProt code: P16311.

Organism: Dermatophagoides farinae (American house dust mite).
Taxonomy: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari; Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Analgoidea; Pyroglyphidae; Dermatophagoidinae; Dermatophagoides.
 
Function: Thiol protease that hydrolyzes proteins, with a preference for Phe or basic residues.
 
Catalytic activity: Reaction=Broad endopeptidase specificity.; EC=3.4.22.65;
Subunit: Monomer. {ECO:0000269|PubMed:19136006}.
Subcellular location: Secreted.
Allergen: Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.
Similarity: Belongs to the peptidase C1 family. {ECO:0000255|PROSITE- ProRule:PRU10088, ECO:0000255|PROSITE-ProRule:PRU10089, ECO:0000255|PROSITE-ProRule:PRU10090}.

Annotations taken from UniProtKB at the EBI.