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PDBsum entry 3rtq

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protein ligands Protein-protein interface(s) links
Immune system PDB id
3rtq

 

 

 

 

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Contents
Protein chains
268 a.a.
96 a.a.
203 a.a.
239 a.a.
Ligands
NAG-NAG
NAG-NAG-BMA-FUL
NAG
H4S
Waters ×126
PDB id:
3rtq
Name: Immune system
Title: Structure of the mouse cd1d-hs44-inkt tcr complex
Structure: Antigen-presenting glycoprotein cd1d1. Chain: a. Fragment: unp residues 19-297. Engineered: yes. Beta-2-microglobulin. Chain: b. Engineered: yes. Valpha14 (mouse variable domain, human constant domain). Chain: c.
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: cd1.1, cd1d, cd1d1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: b2m. Gene: valpha14. Expressed in: escherichia coli.
Resolution:
2.80Å     R-factor:   0.229     R-free:   0.268
Authors: E.D.Yu,D.M.Zajonc
Key ref: J.Kerzerho et al. (2012). Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties. J Immunol, 188, 2254-2265. PubMed id: 22301545
Date:
03-May-11     Release date:   22-Feb-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P11609  (CD1D1_MOUSE) -  Antigen-presenting glycoprotein CD1d1 from Mus musculus
Seq:
Struc:
336 a.a.
268 a.a.
Protein chain
Pfam   ArchSchema ?
P01887  (B2MG_MOUSE) -  Beta-2-microglobulin from Mus musculus
Seq:
Struc:
119 a.a.
96 a.a.
Protein chain
No UniProt id for this chain
Struc: 203 a.a.
Protein chain
No UniProt id for this chain
Struc: 239 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 

 
J Immunol 188:2254-2265 (2012)
PubMed id: 22301545  
 
 
Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties.
J.Kerzerho, E.D.Yu, C.M.Barra, E.Alari-Pahissa, E.Alari-Pahisa, E.Girardi, Y.Harrak, P.Lauzurica, A.Llebaria, D.M.Zajonc, O.Akbari, A.R.Castaño.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23154222 J.Rossjohn, D.G.Pellicci, O.Patel, L.Gapin, and D.I.Godfrey (2012).
Recognition of CD1d-restricted antigens by natural killer T cells.
  Nat Rev Immunol, 12, 845-857.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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