spacer
spacer

PDBsum entry 3ro3
Go to PDB code: 
protein ligands metals Protein-protein interface(s) links
Protein binding PDB id
3ro3

 

 

 

 

Loading ...

 
JSmol PyMol  
Contents
Protein chains
159 a.a.
17 a.a.
Ligands
GOL
EOH
Metals
_CL ×5
Waters ×316
PDB id:
3ro3
Name: Protein binding
Title: Crystal structure of lgn/minscuteable complex
Structure: G-protein-signaling modulator 2. Chain: a. Fragment: unp residues 198-357. Synonym: pins homolog. Engineered: yes. Mutation: yes. Peptide of protein inscuteable homolog. Chain: b. Fragment: unp residues 66-87.
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: gpsm2, lgn, pins. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the sequence naturally occurs in mouse
Resolution:
1.10Å     R-factor:   0.120     R-free:   0.150
Authors: J.Zhu,W.Wen,Y.Shang,Z.Wei,Z.Pan,W.Wang,M.Zhang
Key ref: J.Zhu et al. (2011). LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Gαi/LGN/NuMA pathways. Mol Cell, 43, 418-431. PubMed id: 21816348
Date:
25-Apr-11     Release date:   07-Mar-12    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q8VDU0  (GPSM2_MOUSE) -  G-protein-signaling modulator 2 from Mus musculus
Seq:
Struc: 		 
Seq:
Struc: 		679 a.a.
159 a.a.*
Protein chain
Pfam   ArchSchema ?
Q3HNM7  (INSC_MOUSE) -  Protein inscuteable homolog from Mus musculus
Seq:
Struc: 		 
Seq:
Struc: 		579 a.a.
17 a.a.
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 

 
Mol Cell 43:418-431 (2011)
PubMed id: 21816348  
 
 
LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Gαi/LGN/NuMA pathways.
J.Zhu, W.Wen, Z.Zheng, Y.Shang, Z.Wei, Z.Xiao, Z.Pan, Q.Du, W.Wang, M.Zhang.
 
  ABSTRACT  
 
No abstract given.

 

 

spacer
spacer