PDBsum entry 3rnj

Protein binding

PDB id: 3rnj

Contents

Protein chain

67 a.a.

Ligands

EDT

EDO ×3

IPA

Waters ×86

PDB id:

3rnj

Name:

Protein binding

Title:

Crystal structure of the sh3 domain from irsp53 (baiap2)

Structure:

Brain-specific angiogenesis inhibitor 1-associated protein 2. Chain: a. Fragment: sh3 domain, unp residues 375-436. Synonym: bai-associated protein 2, bai1-associated protein 2, protein bap2, fas ligand-associated factor 3, flaf3, insulin receptor substrate p53/p58, irs-58, irsp53/58, insulin receptor substrate protein of 53 kda, irsp53, insulin receptor substrate p53. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: baiap2. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.50Å R-factor: 0.198 R-free: 0.219

Authors:

P.C.Simister,M.Barilari,J.R.C.Muniz,L.Dente,S.Knapp,F.Von Delft, P.Filippakopoulos,M.Vollmar,A.Chaikuad,J.Raynor,A.Tregubova, C.H.Arrowsmith,A.M.Edwards,J.Weigelt,C.Bountra,S.M.Feller,Structural Genomics Consortium (Sgc)

Key ref:

P.C.Simister et al. Crystal structure of the sh3 domain from irsp53 (baia. To be published, .

Date:

22-Apr-11 Release date: 04-May-11

Protein chain

Q9UQB8  (BAIP2_HUMAN) -  BAR/IMD domain-containing adapter protein 2 from Homo sapiens

Seq: 552 a.a.

Struc: 67 a.a.*

* PDB and UniProt seqs differ at 4 residue positions (black crosses)