UniProt functional annotation for C6E9S6

UniProt code: C6E9S6.

Organism: Escherichia coli (strain B / BL21-DE3).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
Catalytic activity: NADH + quinone = NAD(+) + quinol.
Subunit: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex (By similarity).
Subcellular location: Cell inner membrane; Multi-pass membrane protein (By similarity).
Subcellular location: Membrane; Multi-pass membrane protein (By similarity).
Similarity: Belongs to the complex I subunit 2 family.

Annotations taken from UniProtKB at the EBI.