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PDBsum entry 3rgv

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protein Protein-protein interface(s) links
Immune system PDB id
3rgv

 

 

 

 

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Contents
Protein chains
200 a.a.
236 a.a.
275 a.a.
100 a.a.
13 a.a.
PDB id:
3rgv
Name: Immune system
Title: A single tcr bound to mhci and mhc ii reveals switchable tcr conformers
Structure: Yae62 tcr a chain. Chain: a. Engineered: yes. Mutation: yes. Yae62 tcr b chain. Chain: b. Engineered: yes. H-2 class i histocompatibility antigen, k-b alpha chain. Chain: c.
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: h2-k1, h2-k. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: hi5.
Resolution:
2.90Å     R-factor:   0.205     R-free:   0.254
Authors: S.Dai,E.Huseby,J.Scott-Browne,K.Rubtsova,C.Pinilla,F.Crawford, P.Marrack,L.Yin,J.W.Kappler
Key ref: L.Yin et al. (2011). A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers. Immunity, 35, 23-33. PubMed id: 21683626
Date:
09-Apr-11     Release date:   20-Jul-11    
PROCHECK
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 Headers
 References

Protein chain
No UniProt id for this chain
Struc: 200 a.a.
Protein chain
No UniProt id for this chain
Struc: 236 a.a.
Protein chain
Pfam   ArchSchema ?
P01901  (HA1B_MOUSE) -  H-2 class I histocompatibility antigen, K-B alpha chain from Mus musculus
Seq:
Struc:
369 a.a.
275 a.a.*
Protein chain
Pfam   ArchSchema ?
P01887  (B2MG_MOUSE) -  Beta-2-microglobulin from Mus musculus
Seq:
Struc:
119 a.a.
100 a.a.*
Protein chain
No UniProt id for this chain
Struc: 13 a.a.
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 4 residue positions (black crosses)

 

 
Immunity 35:23-33 (2011)
PubMed id: 21683626  
 
 
A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers.
L.Yin, E.Huseby, J.Scott-Browne, K.Rubtsova, C.Pinilla, F.Crawford, P.Marrack, S.Dai, J.W.Kappler.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
22918468 A.K.Sewell (2012).
Why must T cells be cross-reactive?
  Nat Rev Immunol, 12, 669-677.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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