PDBsum entry 3rg1

Immune system

PDB id: 3rg1

Contents

Protein chains

(+ 1 more) 594 a.a.

397 a.a.

(+ 2 more) 138 a.a.

Ligands

NAG-NAG-BMA ×8

NAG-NAG-BMA-MAN-MAN-MAN-MAN-MAN ×8

PGT ×4

Waters ×37

PDB id:

3rg1

Name:

Immune system

Title:

Crystal structure of the rp105/md-1 complex

Structure:

Cd180 molecule. Chain: a, e, i, m, b, f, j, n. Fragment: ectodomain (unp residues 24-626). Synonym: rp105, radioprotective 105. Engineered: yes. Ly86 protein. Chain: c, d, g, h, k, l, o, p. Fragment: unp residues 21-159. Synonym: md-1.

Source:

Bos taurus. Bovine. Organism_taxid: 9913. Gene: cd180. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: ly86.

Resolution:

2.91Å R-factor: 0.240 R-free: 0.276

Authors:

S.I.Yoon,M.Hong,I.A.Wilson

Key ref:

S.I.Yoon et al. (2011). An unusual dimeric structure and assembly for TLR4 regulator RP105-MD-1. Nat Struct Biol, 18, 1028-1035. PubMed id: 21857663

Date:

07-Apr-11 Release date: 31-Aug-11

Protein chains

A6QNK7  (A6QNK7_BOVIN) -  CD180 molecule from Bos taurus

Seq: 661 a.a.

Struc: 594 a.a.

Protein chain

A6QNK7  (A6QNK7_BOVIN) -  CD180 molecule from Bos taurus

Seq: 661 a.a.

Struc: 397 a.a.*

Protein chains

A4IFT3  (A4IFT3_BOVIN) -  LY86 protein from Bos taurus

Seq: 159 a.a.

Struc: 138 a.a.

* PDB and UniProt seqs differ at 20 residue positions (black crosses)

Nat Struct Biol 18:1028-1035 (2011)

PubMed id: 21857663

An unusual dimeric structure and assembly for TLR4 regulator RP105-MD-1.

S.I.Yoon, M.Hong, I.A.Wilson.

ABSTRACT

No abstract given.