PDBsum entry 3rez

Cell adhesion

PDB id: 3rez

Contents

Protein chains

113 a.a.

Ligands

NAG ×5

PEG ×7

FUL

MAN

Waters ×273

PDB id:

3rez

Name:

Cell adhesion

Title:

Glycoprotein gpib variant

Structure:

Platelet glycoprotein ib beta chain, platelet glycoprotein ix. Chain: a, b, c, d. Synonym: gp-ib beta, gpib-beta, gpibb, antigen cd42b-beta, gp-ix, gpix, glycoprotein 9. Engineered: yes. Other_details: gp1bb and gpix chimeria

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: gp1bb, gp9. Expressed in: cricetulus griseus. Expression_system_taxid: 10029

Resolution:

2.35Å R-factor: 0.214 R-free: 0.259

Authors:

P.A.Mcewan,W.Yang,K.H.Carr,X.Mo,X.Zheng,R.Li,J.Emsley

Key ref:

P.A.McEwan et al. (2011). Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera. Blood, 118, 5292-5301. PubMed id: 21908432

Date:

05-Apr-11 Release date: 15-Feb-12

Protein chains

P13224  (GP1BB_HUMAN) -  Platelet glycoprotein Ib beta chain from Homo sapiens

Seq: 206 a.a.

Struc: 113 a.a.*

Protein chains

P14770  (GPIX_HUMAN) -  Platelet glycoprotein IX from Homo sapiens

Seq: 177 a.a.

Struc: 113 a.a.*

* PDB and UniProt seqs differ at 65 residue positions (black crosses)

Blood 118:5292-5301 (2011)

PubMed id: 21908432

Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera.

P.A.McEwan, W.Yang, K.H.Carr, X.Mo, X.Zheng, R.Li, J.Emsley.

ABSTRACT

No abstract given.