PDBsum entry 3rcp

Membrane protein

PDB id: 3rcp

Contents

Protein chain

100 a.a.

Ligands

GOL

Waters ×65

PDB id:

3rcp

Name:

Membrane protein

Title:

Crystal structure of the fapp1 pleckstrin homology domain

Structure:

Pleckstrin homology domain-containing family a member 3. Chain: a. Fragment: residues 1-99, ph domain. Synonym: ph domain-containing family a member 3, phosphatidylinositol-four-phosphate adapter protein 1, fapp-1, phosphoinositol 4-phosphate adapter protein 1. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: fapp1, plekha3. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.90Å R-factor: 0.233 R-free: 0.255

Authors:

S.Roy,J.He,T.G.Kutateladze

Key ref:

J.He et al. (2011). Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain. J Biol Chem, 286, 18650-18657. PubMed id: 21454700

Date:

31-Mar-11 Release date: 20-Apr-11

Protein chain

Q9HB20  (PKHA3_HUMAN) -  Pleckstrin homology domain-containing family A member 3 from Homo sapiens

Seq: 300 a.a.

Struc: 100 a.a.*

* PDB and UniProt seqs differ at 5 residue positions (black crosses)

J Biol Chem 286:18650-18657 (2011)

PubMed id: 21454700

Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain.

J.He, J.L.Scott, A.Heroux, S.Roy, M.Lenoir, M.Overduin, R.V.Stahelin, T.G.Kutateladze.

ABSTRACT

No abstract given.