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PDBsum entry 3r66
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Viral protein/antiviral protein
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PDB id
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3r66
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PDB id:
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Viral protein/antiviral protein
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Title:
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Crystal structure of human isg15 in complex with ns1 n-terminal region from influenza virus b, northeast structural genomics consortium target ids hx6481, hr2873, and or2
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Structure:
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Non-structural protein 1. Chain: a, b. Fragment: residues 1-103. Synonym: ns1, ns1b. Engineered: yes. Ubiquitin-like protein isg15. Chain: c, d. Synonym: interferon-induced 15 kda protein, interferon-induced 17 kda protein, ip17, ubiquitin cross-reactive protein, hucrp.
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Source:
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Influenza b virus. Organism_taxid: 107412. Strain: b/lee/1940. Gene: ns. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
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Resolution:
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2.30Å
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R-factor:
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0.216
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R-free:
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0.265
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Authors:
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R.Guan,L.C.Ma,R.M.Krug,G.T.Montelione,Northeast Structural Genomics Consortium (Nesg)
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Key ref:
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R.Guan
et al.
The structure of the complex of isg15 and influenza b ns1 protein: implications for the mechanism of sn1-Me inhibition of isg15 conjugation.
To be published,
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Date:
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21-Mar-11
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Release date:
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08-Jun-11
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PROCHECK
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Headers
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References
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Links
