PDBsum entry 3r4d

Cell adhesion/viral protein

PDB id: 3r4d

Contents

Protein chains

199 a.a.

229 a.a.

Ligands

NAG-NAG ×2

NAG ×6

Waters ×68

PDB id:

3r4d

Name:

Cell adhesion/viral protein

Title:

Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor

Structure:

Cea-related cell adhesion molecule 1, isoform 1/2s. Chain: a, c. Fragment: unp residues 35-236. Engineered: yes. Spike glycoprotein. Chain: b, d. Fragment: unp residues 15-296. Synonym: s glycoprotein,e2,peplomer protein. Engineered: yes

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: ceacam1, ceacam1a-2s. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9. Murine coronavirus. Organism_taxid: 694005.

Resolution:

3.10Å R-factor: 0.248 R-free: 0.308

Authors:

G.Q.Peng,D.W.Sun,K.R.Rajashankar,Z.H.Qian,K.V.Holmes,F.Li

Key ref:

G.Peng et al. (2011). Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor. Proc Natl Acad Sci U S A, 108, 10696-10701. PubMed id: 21670291

Date:

17-Mar-11 Release date: 22-Jun-11

Protein chains

P31809  (CEAM1_MOUSE) -  Cell adhesion molecule CEACAM1 from Mus musculus

Seq: 521 a.a.

Struc: 199 a.a.*

Protein chains

Q9J3E7  (Q9J3E7_9BETC) -  Spike glycoprotein from Murine hepatitis virus

Seq: 1324 a.a.

Struc: 229 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)

Proc Natl Acad Sci U S A 108:10696-10701 (2011)

PubMed id: 21670291

Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor.

G.Peng, D.Sun, K.R.Rajashankar, Z.Qian, K.V.Holmes, F.Li.

ABSTRACT

No abstract given.