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PDBsum entry 3r0n
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Cell adhesion
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PDB id
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3r0n
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PDB id:
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| Name: |
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Cell adhesion
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Title:
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Crystal structure of the immunoglobulin variable domain of nectin-2
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Structure:
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Poliovirus receptor-related protein 2. Chain: a. Fragment: ig-like v-type domain residues 32-158. Synonym: herpes virus entry mediator b, herpesvirus entry mediator b, hveb, nectin-2. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: hveb, prr2, pvrl2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
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Resolution:
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1.30Å
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R-factor:
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0.153
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R-free:
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0.173
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Authors:
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U.A.Ramagopal,D.Samanta,S.G.Nathenson,S.C.Almo,New York Structural Genomics Research Consortium (Nysgrc),Atoms-To-Animals: The Immune Function Network (Ifn)
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Key ref:
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D.Samanta
et al.
(2012).
Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion.
Proc Natl Acad Sci U S A,
109,
14836-14840.
PubMed id:
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Date:
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08-Mar-11
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Release date:
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27-Apr-11
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PROCHECK
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Headers
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References
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Q92692
(NECT2_HUMAN) -
Nectin-2 from Homo sapiens
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Seq:
Struc:
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538 a.a.
128 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Proc Natl Acad Sci U S A
109:14836-14840
(2012)
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PubMed id:
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Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion.
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D.Samanta,
U.A.Ramagopal,
R.Rubinstein,
V.Vigdorovich,
S.G.Nathenson,
S.C.Almo.
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ABSTRACT
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Links
