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PDBsum entry 3qzs
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Transcription/nuclear protein
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PDB id
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3qzs
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PDB id:
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| Name: |
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Transcription/nuclear protein
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Title:
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Crystal structure of bptf bromo in complex with histone h4k16ac - form i
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Structure:
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Nucleosome-remodeling factor subunit bptf. Chain: a, b. Synonym: bromodomain and phd finger-containing transcription factor, fetal alz-50 clone 1 protein, fetal alzheimer antigen. Engineered: yes. Mutation: yes. Histone h4. Chain: c, d. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: bptf, fac1, falz. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Xenopus laevis. Clawed frog,common platanna,platanna.
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Resolution:
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1.80Å
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R-factor:
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0.178
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R-free:
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0.230
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Authors:
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H.Li,A.J.Ruthenburg,D.J.Patel
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Key ref:
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A.J.Ruthenburg
et al.
(2011).
Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions.
Cell,
145,
692-706.
PubMed id:
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Date:
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07-Mar-11
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Release date:
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01-Jun-11
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PROCHECK
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Headers
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References
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Q12830
(BPTF_HUMAN) -
Nucleosome-remodeling factor subunit BPTF from Homo sapiens
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Seq:
Struc:
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3046 a.a.
111 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 2 residue positions (black
crosses)
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Cell
145:692-706
(2011)
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PubMed id:
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Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions.
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A.J.Ruthenburg,
H.Li,
T.A.Milne,
S.Dewell,
R.K.McGinty,
M.Yuen,
B.Ueberheide,
Y.Dou,
T.W.Muir,
D.J.Patel,
C.D.Allis.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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B.van Rossum,
W.Fischle,
and
P.Selenko
(2012).
Asymmetrically modified nucleosomes expand the histone code.
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Nat Struct Mol Biol,
19,
1064-1066.
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C.A.Musselman,
M.E.Lalonde,
J.Côté,
and
T.G.Kutateladze
(2012).
Perceiving the epigenetic landscape through histone readers.
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Nat Struct Mol Biol,
19,
1218-1227.
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K.Shiraishi,
H.Kunitoh,
Y.Daigo,
A.Takahashi,
K.Goto,
H.Sakamoto,
S.Ohnami,
Y.Shimada,
K.Ashikawa,
A.Saito,
S.Watanabe,
K.Tsuta,
N.Kamatani,
T.Yoshida,
Y.Nakamura,
J.Yokota,
M.Kubo,
and
T.Kohno
(2012).
A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
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Nat Genet,
44,
900-903.
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S.Liokatis,
A.Stützer,
S.J.Elsässer,
F.X.Theillet,
R.Klingberg,
B.van Rossum,
D.Schwarzer,
C.D.Allis,
W.Fischle,
and
P.Selenko
(2012).
Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events.
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Nat Struct Mol Biol,
19,
819-823.
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
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Links
