UniProt functional annotation for Q9NBA8



	UniProt functional annotation for Q9NBA8

UniProt code: Q9NBA8.

Organism: Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii).

Taxonomy: Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda; Coleoidea; Decapodiformes; Teuthida; Myopsina; Loliginidae; Doryteuthis.

Function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. {ECO:0000256|PIRNR:PIRNR000956}.

Catalytic activity: Reaction=a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5- bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2- diacyl-sn-glycerol + H(+); Xref=Rhea:RHEA:33179, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17815, ChEBI:CHEBI:58456, ChEBI:CHEBI:203600; EC=3.1.4.11; Evidence={ECO:0000256|PIRNR:PIRNR000956, ECO:0000256|RuleBase:RU361133};

Annotations taken from UniProtKB at the EBI.


Organism:		Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii).
Taxonomy:		Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda; Coleoidea; Decapodiformes; Teuthida; Myopsina; Loliginidae; Doryteuthis.



Function:		The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. {ECO:0000256\|PIRNR:PIRNR000956}.


Catalytic activity:		Reaction=a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5- bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2- diacyl-sn-glycerol + H(+); Xref=Rhea:RHEA:33179, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17815, ChEBI:CHEBI:58456, ChEBI:CHEBI:203600; EC=3.1.4.11; Evidence={ECO:0000256\|PIRNR:PIRNR000956, ECO:0000256\|RuleBase:RU361133};