PDBsum entry 3qq8

Transport protein/apoptosis

PDB id: 3qq8

Contents

Protein chains

177 a.a.

80 a.a.

Metals

_CL

Waters ×146

PDB id:

3qq8

Name:

Transport protein/apoptosis

Title:

Crystal structure of p97-n in complex with faf1-ubx

Structure:

Transitional endoplasmic reticulum atpase. Chain: a. Fragment: unp residues 2-187. Synonym: ter atpase, 15s mg(2+)-atpase p97 subunit, valosin- containing protein, vcp. Engineered: yes. Fas-associated factor 1. Chain: b. Fragment: unp residues 568-650.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: vcp. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: faf1, ubxd12, ubxn3a, cgi-03. Expression_system_taxid: 562

Resolution:

2.00Å R-factor: 0.169 R-free: 0.210

Authors:

P.Haenzelmann,H.Schindelin

Key ref:

P.Hänzelmann et al. (2011). Hierarchical binding of cofactors to the AAA ATPase p97. Structure, 19, 833-843. PubMed id: 21645854

Date:

15-Feb-11 Release date: 22-Jun-11

Protein chain

P55072  (TERA_HUMAN) -  Transitional endoplasmic reticulum ATPase from Homo sapiens

Seq: 806 a.a.

Struc: 177 a.a.

Protein chain

Q9UNN5  (FAF1_HUMAN) -  FAS-associated factor 1 from Homo sapiens

Seq: 650 a.a.

Struc: 80 a.a.

Enzyme reactions

• Enzyme class 2: Chain A: E.C.3.6.4.6 - vesicle-fusing ATPase.
• Reaction: ATP + H2O = ADP + phosphate + H⁺
• Enzyme class 3: Chain B: E.C.?

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

Structure 19:833-843 (2011)

PubMed id: 21645854

Hierarchical binding of cofactors to the AAA ATPase p97.

P.Hänzelmann, A.Buchberger, H.Schindelin.

ABSTRACT

No abstract given.